tecovirimat will increase the amount or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse consequences if coadministered with delicate substrates of those enzymes.diazepam will boost the degree or effect of isavuconazonium sulfa